Sam R. J. Hoare, Ph.D.
Pharmacology data analyst and consultant
Analytical pharmacology ■ Kinetics ■ Signaling ■ GPCR ■ Ligand binding ■ Allosteric modulation
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Founder & Consultant @ Pharmechanics LLC
Owego, NY, USA
Dr. GPCR Ecosystem Member since August 2020
I am a seasoned GPCR drug discovery scientist, with 15 years of experience in the pharmaceutical industry and a track record in developing new ways to analyze and understand GPCR pharmacology. I am known particularly for applying kinetics to the discovery and development of improved GPCR therapeutics, and for developing new analytical frameworks to quantify signaling kinetics. In 2015, I founded Pharmechanics LLC, a consultancy that provides pharmacology data analysis tools and support and strategic consulting for pharmaceutical, life science, and scientific research organizations.
I am known for demystifying complicated and newly-emerging pharmacology concepts, enabling them to be applied by investigators and project teams to drug discovery and receptor research. I completed postdoctoral training at the National Institute of Mental Health, researching pharmacological mechanisms of Class B GPCRs, and obtained my Ph.D. in biochemistry, studying allosteric modulation of dopamine receptors, from the University of Kent, United Kingdom.
Expertise
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Kinetics of binding and signaling
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Family B GPCR pharmacology
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Analytical pharmacology
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Industrial pharmacology
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Allosteric modulation
Publications
