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Meet Dr. GPCR Summit Partners

Preliminary Schedule

Dr. GPCR Summit 2021

 
 

Please note:

   

• The program is complete! Don't miss a chance to listen to 25+ scientific talks, which will only be available for those who registered during the Summit. 

• Get your All-Access ticket before they're gone by visiting Eventbrite today! 

• Got your All-Access ticket already? Check your inbox this week, you'll be able to invite a friend or colleague to join the Summit for Free!

• Proceeds from the ticket sales will be used to provide the best 3 trainee talks with fantastic prizes including a personalized autographed copy of Dr. Lefkowitz's biography.

• Present a pre-recorded talk and get free access to the entire Summit! Hurry, the deadline to submit your talk is Friday, September 10th, 2021 at midnight EST.

• If you're facing financial difficulties or are a trainee who would like to attend but can't submit a pre-recorded talk reach out to us now!

    

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Live talks

    

• Dr. GPCR Summit Presents GPCRdb Resources

  - Dr. David Gloriam, Dr. Albert Kooistra, Gáspár Pándy-Szekeres
  - Monday, 09/13/2021 @ 10:00 AM - EST
  - Reserve your spot 

   

• CXCR4 heteromers as novel cancer targets

  - Dr. Juan Jose Fung & Dr. Pina Cardarelli
  - Monday, 09/13/ 2021 @ 1:00 PM - EST
  - Reserve your spot  

  

• Unconventional GPCR Signaling in the Hedgehog Pathway

  - Dr. Ben Myers
  - Monday, 09/13/2021 @ 2.00 PM - EST
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• The Phosphorylation Barcode as a Mechanism of Biased β-arrestin 2 Recruitment and Conformation at CXCR3

  - Dylan Eiger 
  - Monday, 09/13/2021 @ 3.00 PM - EST
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• A distinct activation mechanism in GPCR dimers: Insights from cryo-EM snapshots of the entire Class D1 GPCR activation pathway

  - Vaithish Velazhahan
  - Monday, 09/13/2021 @ 4:00 PM - EST
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• Heat Shock Protein 90 is a Novel Opioid Receptor Signaling Regulator that can be Targeted to Improve Opioid Therapy

  - Dr. John Streicher 
  - Monday, 09/13/ 2021 @ 5:00 PM - EST
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• Through the Looking-Glass: Structure-Based Drug Discovery across the GPCRome

  - Dr. Chris de Graaf 
  - Tuesday, 09/14/2021 @ 8:00 AM - EST
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• Designer G protein-coupled receptors as tools to identify novel targets for antidiabetic and anti-obesity drugs

  - Dr. Jürgen Wess
  - Tuesday, 09/14/2021 @ 9:00 AM - EST
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• "Toolboxing" solid-state NMR spectroscopy for GPCR studies

  - Dr. Jiafei Mao 
  - Tuesday, 09/14/2021 @ 10:00 AM - EST
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• GPCRomics: Identifying novel GPCR targets in health and disease

  - Dr. Paul Insel 
  - Tuesday, 09/14/2021 @ 11:00 AM - EST
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• A Funny Thing Happened at the Dr. GPCR Summit

  - Dr. Bob Lefkowitz and Dr. Randy Hall
  - Tuesday, 09/14/2021 @ 1:00 PM - EST
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• Twist Biopharma: Synthetic DNA Technologies Enable Fast and Responsive anti-GPCR Antibody Discovery and Optimization

  - Dr. Aaron K. Sato 
  - Tuesday, 09/14/2021 @ 3:00 PM - EST
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• Advancing GPCR drug discovery with bioSensAll® platform technology

  - Dr. Meriem Semache
  - Wednesday, 09/15/2021 @ 10:00 AM - EST
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• GPCR activation mechanisms across classes and macro/micro scales

  - Dr. David Gloriam 
  - Wednesday, 09/15/2021 @ 2:00 PM - EST
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• Hydroxycarboxylic acid receptor 3 and GPR84 signaling with potential implications for immune cell function

  - Dr. Claudia Stäubert 
  - Wednesday, 09/15/2021 @ 3:00 PM - EST
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• Engineering a human GPCR to create self-tunable engineered yeast probiotics for the treatment of inflammatory bowel disease

  - Dr. Benjamin Scott    
  - Wednesday, 09/15/2021 @ 4:00 PM - EST
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• The challenges of targeting RXFP1, the receptor for the heart failure drug candidate relaxin, with peptide mimetics and small molecules

  - Dr. Ross Bathgate   
  - Wednesday, 09/15/2021 @ 5:00 PM - EST
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• Profiling of GPCR complexes

  - Dr. Kevin Pfleger
  - Thursday, 09/16/ 2021 @ 8:00 AM - EST
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• Phosphorylation of the M1 muscarinic acetylcholine receptor protects from neurodegenerative disease

  - Miriam Scarpa 
  - Thursday, 09/16/ 2021 @ 9:00 AM - EST
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• Innate Proximity: Utilizing the Inherent Physicality of Receptor Interactions for Drug Development

  - Dr. Ajay Yekkirala 
  - Thursday, 09/16/ 2021 @ 10:00 AM - EST
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• Chaperoning G protein-coupled receptors

  - Dr. Ya-Xiong Tao 
  - Thursday, 09/16/ 2021 @ 11:00 AM - EST
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• Where a Ph.D. Can Lead

  - Dr. Brian Arey, Dr. Samuel Hoare, Dr. Stephanie Val, Dr. Ajay Yekkirala
  - Thursday, 09/16/ 2021 @ 1:00 PM - EST
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• FR900359: nature’s weapon and treasure trove for basic and translational research

  - Dr. Evi Kostenis
  - Friday, 9/17/2021 @ 1.00 PM - EST
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• Molecular basis of adhesion GPCR activation

  - Dr. Demet Araç 
  - Friday, 09/17/2021 @ 2:00 PM - EST
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• Structure-guided drug discovery

  - Dr. Bryan Roth 
  - Friday, 09/17/2021 @ 3:00 PM - EST
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• Nanobody tethering to dissect GPCR pharmacology

  - Dr. Ross Cheloha 
  - Friday, 09/17/ 2021 @ 4:00 PM - EST
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• Structure and dynamics of GPCRs: lessons from cryo-EM

  - Dr. Patrick Sexton
  - Friday, 09/17/ 2021 @ 5:00 PM - EST
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Pre-recorded talks

   

• Marginal phenotypes with orphan GPCRs: a GPR37L1 case study*

  - Dr. Nicola Smith

   

• Integrating computational modeling and experimental data to unravel the molecular and intracellular effects of a disease-linked variant of the oxytocin receptor*

  - Dr. Mercedes Alfonso-Prieto

      

• A general method for quantifying ligand binding to unmodified receptors using Gaussia luciferase

  - Dr. András Tóth

   

• Follicle-stimulating hormone induces lipid droplets via Gai and beta-arrestin in an endometrial cancer cell line*

  - Dr. Niamh Sayers

  

• Assessing Serotonin 1A Receptor Expression and Function in Adult Fmr1 Knockout Mice, a Preclinical Model of Fragile X Syndrome*

  - Dr. Tanishka Saraf

     

• Applying structure-based ligand design to low-resolution GPCR structures

  - Dr. Antonella Di Pizio

   

• Celtarys Research: Innovative Chemistry to Illuminate Biology

  - Sonia Martínez Arca

    

• “Better Medicine, One Assay at a Time” Save time, energy, and cost from Target to IND

  - Dr. Lisa Minor

    

• Healing is a matter of time

  - Dr. Stuart Maudsley

  

• Construction of GPCR heteromer database and validation of CXCR4-GPCRx heteromers* 

  - Dr. Jae-Yeon Jeong

    

  

Canceled talk

     

• Examining the mechanism of action of CXCR2 intracellular NAMs

  - Desislava Nesheva 
  - Thursday, 09/16/ 2021 @ 10:00 AM - EST
  - Reserve your spot