Dr. GPCR Ecosystem   -   Dr. GPCR Summit   -   Dr. GPCR Summit 2021 Full Schedule

---

Meet Dr. GPCR Summit Partners

Schedule & Talks

Dr. GPCR Summit 2021

   
- For the best experience use Chrome or Firefox browsers -
- Make sure you join us on Microsoft Teams to chat with speakers all week long -
- Make sure you have a profile picture set both on Zoom & Microsoft Teams- 

 

Live talks

    

• Dr. GPCR Summit Presents GPCRdb Resources

  - Dr. David Gloriam, Dr. Albert Kooistra, Gáspár Pándy-Szekeres
  - Monday, 09/13/2021 @ 10:00 AM - EST

 

• CXCR4 heteromers as novel cancer targets

  - Dr. Juan Jose Fung & Dr. Pina Cardarelli
  - Monday, 09/13/ 2021 @ 1:00 PM - EST

  

• Unconventional GPCR Signaling in the Hedgehog Pathway

  - Dr. Ben Myers
  - Monday, 09/13/2021 @ 2.00 PM - EST

 

• The Phosphorylation Barcode as a Mechanism of Biased β-arrestin 2 Recruitment and Conformation at CXCR3

  - Dr. Dylan Eiger 
  - Monday, 09/13/2021 @ 3.00 PM - EST

 

• A distinct activation mechanism in GPCR dimers: Insights from cryo-EM snapshots of the entire Class D1 GPCR activation pathway

  - Dr. Vaithish Velazhahan
  - Monday, 09/13/2021 @ 4:00 PM - EST

 

• Heat Shock Protein 90 is a Novel Opioid Receptor Signaling Regulator that can be Targeted to Improve Opioid Therapy

  - Dr. John Streicher 
  - Monday, 09/13/ 2021 @ 5:00 PM - EST

   

---

• Through the Looking-Glass: Structure-Based Drug Discovery across the GPCRome

  - Dr. Chris de Graaf 
  - Tuesday, 09/14/2021 @ 8:00 AM - EST

 

• Designer G protein-coupled receptors as tools to identify novel targets for antidiabetic and anti-obesity drugs

  - Dr. Jürgen Wess
  - Tuesday, 09/14/2021 @ 9:00 AM - EST

 

• "Toolboxing" solid-state NMR spectroscopy for GPCR studies

  - Dr. Jiafei Mao 
  - Tuesday, 09/14/2021 @ 10:00 AM - EST

      

• GPCRomics: Identifying novel GPCR targets in health and disease

  - Dr. Paul Insel 
  - Tuesday, 09/14/2021 @ 11:00 AM - EST

     

• A Funny Thing Happened at the Dr. GPCR Summit

  - Dr. Bob Lefkowitz and Dr. Randy Hall
  - Tuesday, 09/14/2021 @ 1:00 PM - EST

    

• Twist Biopharma: Synthetic DNA Technologies Enable Fast and Responsive anti-GPCR Antibody Discovery and Optimization

  - Dr. Aaron K. Sato 
  - Tuesday, 09/14/2021 @ 3:00 PM - EST

      

---

• Advancing GPCR drug discovery with bioSensAll® platform technology

  - Dr. Meriem Semache
  - Wednesday, 09/15/2021 @ 10:00 AM - EST

 

• GPCR activation mechanisms across classes and macro/micro scales

  - Dr. David Gloriam 
  - Wednesday, 09/15/2021 @ 2:00 PM - EST

 

• Hydroxycarboxylic acid receptor 3 and GPR84 signaling with potential implications for immune cell function

  - Dr. Claudia Stäubert 
  - Wednesday, 09/15/2021 @ 3:00 PM - EST

 

• Engineering a human GPCR to create self-tunable engineered yeast probiotics for the treatment of inflammatory bowel disease

  - Dr. Benjamin Scott    
  - Wednesday, 09/15/2021 @ 4:00 PM - EST

 

• The challenges of targeting RXFP1, the receptor for the heart failure drug candidate relaxin, with peptide mimetics and small molecules

  - Dr. Ross Bathgate   
  - Wednesday, 09/15/2021 @ 5:00 PM - EST

     

---

• Profiling of GPCR complexes

  - Dr. Kevin Pfleger
  - Thursday, 09/16/ 2021 @ 8:00 AM - EST

 

• Phosphorylation of the M1 muscarinic acetylcholine receptor protects from neurodegenerative disease

  - Dr. Miriam Scarpa 
  - Thursday, 09/16/ 2021 @ 9:00 AM - EST

          

• Innate Proximity: Utilizing the Inherent Physicality of Receptor Interactions for Drug Development

  - Dr. Ajay Yekkirala 
  - Thursday, 09/16/ 2021 @ 10:00 AM - EST

      

• Chaperoning G protein-coupled receptors

  - Dr. Ya-Xiong Tao 
  - Thursday, 09/16/ 2021 @ 11:00 AM - EST

 

• Where a Ph.D. Can Lead

  - Dr. Brian Arey, Dr. Samuel Hoare, Dr. Stephanie Val, Dr. Ajay Yekkirala
  - Thursday, 09/16/ 2021 @ 1:00 PM - EST

      

---

• FR900359: nature’s weapon and treasure trove for basic and translational research

  - Dr. Evi Kostenis
  - Friday, 9/17/2021 @ 1.00 PM - EST

 

• Molecular basis of adhesion GPCR activation

  - Dr. Demet Araç 
  - Friday, 09/17/2021 @ 2:00 PM - EST

    

• Structure-guided drug discovery

  - Dr. Bryan Roth 
  - Friday, 09/17/2021 @ 3:00 PM - EST

 

• Nanobody tethering to dissect GPCR pharmacology

  - Dr. Ross Cheloha 
  - Friday, 09/17/ 2021 @ 4:00 PM - EST

 

• Structure and dynamics of GPCRs: lessons from cryo-EM

  - Dr. Patrick Sexton
  - Friday, 09/17/ 2021 @ 5:00 PM - EST

     
   

Pre-recorded talks

   

• Marginal phenotypes with orphan GPCRs: a GPR37L1 case study*

  - Dr. Nicola Smith

   

• Integrating computational modeling and experimental data to unravel the molecular and intracellular effects of a disease-linked variant of the oxytocin receptor*

  - Dr. Mercedes Alfonso-Prieto

      

• A general method for quantifying ligand binding to unmodified receptors using Gaussia luciferase

  - Dr. András Tóth

   

• Follicle-stimulating hormone induces lipid droplets via Gai and beta-arrestin in an endometrial cancer cell line*

  - Dr. Niamh Sayers

  

• Assessing Serotonin 1A Receptor Expression and Function in Adult Fmr1 Knockout Mice, a Preclinical Model of Fragile X Syndrome*

  - Dr. Tanishka Saraf

     

• Applying structure-based ligand design to low-resolution GPCR structures

  - Dr. Antonella Di Pizio

   

• Celtarys Research: Innovative Chemistry to Illuminate Biology

  - Sonia Martínez Arca

    

• “Better Medicine, One Assay at a Time” Save time, energy, and cost from Target to IND

  - Dr. Lisa Minor

    

• Healing is a matter of time

  - Dr. Stuart Maudsley

  

• Construction of GPCR heteromer database and validation of CXCR4-GPCRx heteromers* 

  - Dr. Jae-Yeon Jeong

  
   

Canceled talk

     

• Examining the mechanism of action of CXCR2 intracellular NAMs

  - Desislava Nesheva 
  - Thursday, 09/16/ 2021 @ 10:00 AM - EST
  - Reserve your spot